CYNTHIA BURROWS
Distinguished Professor
Chemistry
Orcid identifier0000-0001-7253-8529 (opens in a new tab)
- Distinguished ProfessorChemistry
- University of Utah, Chemistry, 315 S. 1400 East, Salt Lake City, UT, 84112-0850, United States
RESEARCH INTERESTS
We investigate nucleic acid chemistry ranging from oxidative damage to DNA, DNA repair and mutagenesis leading to cancer. In cell-based studies we found evidence of oxidized guanine lesions playing an epigenetic role in gene promoters involving G-quadruplexes. We are developing methods, including single-molecule nanopores, to sequence DNA and RNA for modifications (8-oxoG, pseudouridine and m6A), the latter being co-located with G-quadruplexes in mRNA and in viral RNA.
GRANTS
- EXTERNAL GRANT OR CONTRACTDecoding the oxidative epistructuromic RNA regulation in cancer and neurological diseasesHorizon-Synergy Grant1 Jan 2026
- EXTERNAL GRANT OR CONTRACTHIGH-RESOLUTION PSEUDOURIDINE AND M6A SEQUENCING THROUGH ADVANCED NANOPORE ADDUCT ANALYSIS CHARACTERIZATIONELECTRONIC BIOSCIENCE INC1 Jun 2025 - 31 May 2026
- EXTERNAL GRANT OR CONTRACT“Chemical Modifications in Regulatory Regions of DNA and RNA,”National Institutes of Health1 Jun 2022 - 31 May 2027People funded by this grant:
- Fleming A
- EXTERNAL GRANT OR CONTRACTCHEMICAL BIOLOGY OF DNA AND RNA MODIFICATIONS IN RESPONSE TO OXIDATIVE STRESS1 Jun 2022 - 31 May 2027
- EXTERNAL GRANT OR CONTRACTREDOX PHOTOCHEMISTRY OF DNANATIONAL SCIENCE FOUNDATION8 Jan 2015 - 31 Dec 2019
- EXTERNAL GRANT OR CONTRACTOXIDIZED PURINE LESIONS IN DNANIH NATIONAL CANCER INSTITUTE5 Jan 2015 - 31 Dec 2021
- EXTERNAL GRANT OR CONTRACTEBS SUB - RNA MODIFICATIONSELECTRONIC BIOSCIENCE INC9 Jan 2014 - 31 Dec 2016
- EXTERNAL GRANT OR CONTRACTSMALL MOLECULE INHIBITORSARMY MEDICAL RESEARCH ACQUISIT6 Jan 2014 - 31 Dec 2017
- EXTERNAL GRANT OR CONTRACTOXIDIZED BASES IN DNA AND RNANATIONAL SCIENCE FOUNDATION1 Feb 2012 - 31 Dec 2016
- EXTERNAL GRANT OR CONTRACTNANOPORE DETECTION OF DNA DMGNIH NATIONAL INST OF GENERAL M6 Jan 2011 - 31 Dec 2015
- EXTERNAL GRANT OR CONTRACTBURROWS:CHEM&BIO OF OXIDIZED PNIH NATIONAL CANCER INSTITUTE7 Jan 2010 - 31 Dec 2015
- EXTERNAL GRANT OR CONTRACTBURROWS-RAPID METHYLATION MAPPELECTRONIC BIOSCIENCE INC1 Jan 2010 - 31 Dec 2012
- EXTERNAL GRANT OR CONTRACT50 KBASE DNA SEQUENCINGELECTRONIC BIOSCIENCE INC8 Mar 2009 - 5 Feb 2012
- EXTERNAL GRANT OR CONTRACT99.99% ACCURACY DIRECT DNA SEQELECTRONIC BIOSCIENCE INC1 Jan 2009 - 31 Dec 2013
- EXTERNAL GRANT OR CONTRACTWORKSHOP ON NUCLEIC ACID CHEMGILEAD8 Mar 2008 - 8 Feb 2009
- EXTERNAL GRANT OR CONTRACTCHEMICAL MODIFICATIONS OF SIRNUNIVERSITY OF CALIFORNIA DAVIS4 Jan 2007 - 31 Dec 2012
- EXTERNAL GRANT OR CONTRACTOXIDIZED PURINE LESIONS IN DNANIH NATIONAL CANCER INSTITUTE7 Jan 2006 - 31 Dec 2010
- EXTERNAL GRANT OR CONTRACTNUCLEIC ACIDNATIONAL SCIENCE FOUNDATION8 Jan 2005 - 31 Dec 2008
- EXTERNAL GRANT OR CONTRACTRNA REGULATION BY PKRNIH NATIONAL INST OF GENERAL M5 Jan 2003 - 31 Dec 2008
- EXTERNAL GRANT OR CONTRACTOXIDIZED 8-0X0-GDHHS/NIH/NCI1 Apr 2002 - 31 Dec 2006
- EXTERNAL GRANT OR CONTRACTMETAL COMPLEXES FOR RIBOZYMESDHHS/NIH/NIGMS7 Jan 2000 - 31 Dec 2003
- EXTERNAL GRANT OR CONTRACTNUCLEIC ACID OXIDATIONNATL SCIENCE FNDN1 Jan 1999 - 31 Dec 2012
- EXTERNAL GRANT OR CONTRACTNATURAL PRODUCTS WORKSHOPNATL SCIENCE FNDN6 Jan 1997 - 2 Mar 1999
- EXTERNAL GRANT OR CONTRACTUS-FRANCE COOPNATL SCIENCE FNDN1 Jan 1997 - 31 Dec 2003
- EXTERNAL GRANT OR CONTRACTNICKEL COMPLEXES WITH DNADHHS/NIH/NIGMS12 Jan 1996 - 31 Dec 2001