Dr. Shiu was recruited to the Department of Bioengineering at the University of Utah in 2002, and she has carried on the University's tradition of excellence and innovation in the area of cardiovascular devices, making unique and important contributions in this area. The excellence of her research was recognized by the review body of the American Heart Association National Innovative Research Grant Program to give her a top 3 percentile score in 2008, which is truly outstanding. Dr. Shiu's papers are well-cited, and she has received several highly competitive grants as a principal investigator. At the University of Utah, Dr. Shiu has expanded her research from basic molecular cell biology focused on endothelial mechanotransduction to more translational research in dialysis vascular access, stents, and vascular remodeling/regeneration. Dr. Shiu has a diversified research background that puts her in a unique position in translational research. Because of her new focus on translational research, Dr. Shiu decided to pursue a full-time faculty position in the Department of Medicine, starting in August 2010. She wanted to commit more time to her research projects, and she planned to get more involved in clinical studies/trials. Currently Dr. Shiu's academic home is the Division of Nephrology & Hypertension in the Department of Medicine. Her laboratory uses experimental and computational techniques to conduct clinical and laboratory research related to (i) hemodialysis vascular access, (ii) vascular dysfunctions and pathomechanics in patients with CKD, CVD and PVD, and (iii) mechanobiology. She has received research funding as a PI from the National Institutes of Health (R01), Department of Veterans Affairs (Merit Review), Western Institute for Biomedical (Veterans) Research, American Heart Association, National Kidney Foundation of Utah & Idaho, other funding agencies, and the industry. Her research papers have been published in top-tier journals and selected as cover figures.